Method for eliminating GC bias caused by high-throughput sequencing and detecting chromosome copy number mutation (patent No. ZL201410394930.X)

Through comparing and correcting the gene sequence obtained by processing the human genome using high-throughput sequencing technology, this method performs a T test between chromosomes to determine whether there is euploid variation in the chromosome in the mixed sample.
This patent well solves the technical problem of GC bias caused by high-throughput sequencing, thus making it possible to apply high-throughput sequencing in the detection of chromosome copy number variation in mixed samples.